Mrs. Brisby (also known as Bris and Elizabeth Jennifer Brisby) is a kind and very beautiful mouse who is the widowed wife of Jonathan Brisby. She lived with four children (Timmy, Martin, Teresa and Cynthia) and best friends with Jeremy the Crow. She is Fievel and Tanya's adoptive mother after the death of their parents.

Bris is also the title character of the crossover series with the same name.